Method of Housing and Transfer and Experimental Autoimmune Encephalomyelitis: An Experimental Study on C57BL/6
نویسندگان
چکیده
منابع مشابه
method of housing and transfer and experimental autoimmune encephalomyelitis: an experimental study on c57bl/6
results our data showed that the eae induction in group one was significantly more successful than group two (with the mean score > 3). conclusions although the eae is still a scientific method to induce ms in rodents, it requires more attention to environmental factors that might influence the result. the mechanisms of these factors are unknown, but it seems that the role of housing environmen...
متن کاملMethod of Housing and Transfer and Experimental Autoimmune Encephalomyelitis: An Experimental Study on C57BL/6
1Department of Basic Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, IR Iran 2Department of Medical Basic Sciences, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, IR Iran 3Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, IR Iran 4Multiple Sclerosis Research Center, Neuroscience Institute, Sina Hospital, Te...
متن کاملConventional Housing Conditions Attenuate the Development of Experimental Autoimmune Encephalomyelitis
BACKGROUND The etiology of multiple sclerosis (MS) has remained unclear, but a causative contribution of factors outside the central nervous system (CNS) is conceivable. It was recently suggested that gut bacteria trigger the activation of CNS-reactive T cells and the development of demyelinative disease. METHODS C57BL/6 (B6) mice were kept either under specific pathogen free or conventional ...
متن کاملImmunomodulatory Effect of Mesenchymal Stem Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: A Review Study
Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system that may lead to disability of the patient. Current MS treatment regimens are still insufficient and research is conducted for developing more effective therapies capable of targeting neurodegeneration, inflammation, and demyelination. Recent results of experimental and clinical studies in ...
متن کاملExperimental autoimmune encephalomyelitis Experimental aspects of EAE
myelinating disease of the central nervous system (CNS) that takes a relapsing–remitting or a progressive course (reviewed in Refs 1,2). Its counterpart in the peripheral nervous system (PNS) is chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) (reviewed in Ref. 3). In addition, there are acute, monophasic disorders, such as the inflammatory demyelinating polyradiculoneuropathy t...
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ژورنال
عنوان ژورنال: Thrita
سال: 2014
ISSN: 2352-0612,2352-0620
DOI: 10.5812/thrita.22187